报告摘要：Technologies to manipulate or assembly molecules at extremely high levels of spatial confinement could open a door to many fundamental research and practical applications, particularly in the biomedical field. Nanowires and nanochannels are the two most commonly employed elements in nanoscale systems. However, it is difficult and/or expensive to fabricate nanowires/channels with the diameter/pore size smaller than 5 nm without defects. We recently developed a novel, simple and low-cost DNA combing and imprinting (DCI) method capable of forming an array of laterally ordered nanowires or nanochannels. Applications of DCI include nanochannel electroporation (NEP) which allow nucleic acid transfection of cells with precise control over dose and timing will be discussed.